Hepcidin Overexpression and Hypotestosteronemia in Middle-Aged Atherosclerosis Patients

Abstract

Atherosclerosis is a dangerous condition that can endanger the lives of both men and women. As people age, their risk of developing this illness rises. In order to evaluate the vital markers pretentious by Cardiopathy, such as hepcidine, iron, and sex hormones. Forty men and twenty women with atherosclerosis, ages 45 to 75, took part in the current study. The control group, on the other hand, included fifteen healthy men and fifteen healthy females. The data showed that the patients' hepcidin levels differed considerably from those of the healthy individuals. The study's findings also demonstrated that males with atherosclerosis have low levels of the sex hormone testosterone. Although males with atherosclerosis are more prone to experience sexual dysfunction as they age, the current study found that individuals with atherosclerosis are more vulnerable to oxidative stress because of higher iron levels.